2022-05-10

Fascioliasis is considered as a neglected zoonotic disease of ruminants. This disease is caused by two species of Fasciola (F.) namely Fasciola hepatica and F. gigantica. They are distributed in more than 70 countries except Antarctica, in areas where sheep and cattle are reared (WHO 2016; CDC 2o19). This disease was first recorded as early as 2000 BC. Fasciola spp. cause serious pathological effects to livestock (Abbas et al. 2019). The number of infected sheep exceeds 250 million and about 300 million cattle are infected globally with fascioliasis. The disease cause losses exceeding 3.2 billion $ yearly, due to decrease in milk and meat production and an increase in mortality rate in addition to liver condemnation and expenditure of anthelminthic (Hillyer and Apt 1997; Jaja et al. 2017).