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البحوث العلمية

2022

The Impact of Toxoplasma gondii Antibodies on HaematologicalParameters among Women in Zakho District/ Iraq

2022-10
HIV Nursing (القضية : 2) (الحجم : 22)
Background: The correlation between anti-Toxoplasma gondii seropositivity and haematological parameters are poorly understood. Therefore, this investigation explores to determine the seropositivity of anti-Toxoplasma IgG and IgM Antibodies among females of different status in addition to investigating the effects of toxoplasmosis on some haematological parameters. Methods: A total 125 women were contributed, each blood samples were evaluated for toxoplasmosis and haematological components. Results: The study revealed a total rate of anti-Toxoplasma Abs as 17.6% (22/125), 12.8% (16/125) for IgG Abs and 4.8% (6/125) for IgM Abs. Married, pregnant and female in 3rd trimester showed the highest rates for anti-Toxoplasma IgG Abs. Moreover, the maximum rate of IgG antibodies was recorded among females with A- and B- blood groups at equal rates (n=1, 33.3%) for each of them. As regarding to ELISA IgM, it was only recorded among AB+ and A+. As well, among seropositive IgG cases significant association was observed with the different levels of Haemoglobin (Hb) (P-value =0.052) while, for seropositive IgM cases significant differences was only found among mean number of red blood cells (RBC) (P-value =0.013). Conclusion: T.gondii has vital influence on health, thus, screening pregnant females especially at early stages of pregnancy is recommended. Besides, focusing on performing CBCs, biochemical and hormonal tests for pregnant females, also, further investigation and improvement in the diagnostic methods are crucial.
2021

Serodiagnosis of Toxoplasmosis by Using ELISA and IgG Avidity Test in Relation to Some Risk Factors among Women at Childbearing Age in Zakho City KurdistanRegion of Iraq

2021-08
Al-Qadisiyah Journal of Pure Science (القضية : 4) (الحجم : 26)
This study intended to evaluate the seroprevalence of anti-Toxoplasma IgG and IgM antibodies in the sera of 630 women at childbearing age, and to link the outcomes with some risk factors. The enrolled women visited Zakho Maternity Hospital from July 2018 to July 2019. Their ages ranged from 15 to 45 years. All samples were examined using ELISA to detect immunoglobulin G and M, in addition to performing IgG Avidity test for seropositive pregnant women. The differences between seropositivity and age was significant (p<0.05), the highest rate (20.43%) for anti-Toxoplasma IgG antibodies in the age group 33-38 years. Women who had more contact with cats showed higher IgG and IgM seropositivity rates (16.45% and 1.26%, respectively). Married women had higher IgG Abs seropositivity than single ones (12.52% vs 6.31%, respectively), moreover, only married women were seropositive for IgM Abs. Pregnant women presented higher IgG Abs seropositivity than non- pregnant (15.21% versus 10.49%), with almost equal seropositivity for IgM Abs (0.65% and 0.86%, respectively). Anti-Toxoplasma IgG Abs seropositivity was higher in women underwent miscarriages than those with normal pregnancies (18.44 vs. 8.81%), however IgM Abs was only found among women who had miscarriages (0.97%). Women with triple miscarriages presented the highest IgG Abs seropositivity (37.03%). Chronic infection was found in 68.75% of pregnant women, whereas acute infection was found in 31.25 %. Following up the pregnancy resulted in 15 healthy births, 9 miscarriages, and 10 women did not show up. The finding of this study demonstrates the relationship between toxoplasmosis and risk factors in women at childbearing age, with the aims of decreasing infection rates through the introducing of health education programs and the application of hygienic measures in the community by health authority.

Serodiagnosis of Toxoplasmosis by Using ELISA and IgG Avidity Test in Relation to Some Risk Factors among Women at Childbearing Age in Zakho City, Duhok Province/ Iraq.

2021-08
Al-Qadisiyah Journal of Pure Science (القضية : 4) (الحجم : 26)
This study intended to evaluate the seroprevalence of anti-Toxoplasma IgG and IgM antibodies in the sera of 630 women at childbearing age, and to link the outcomes with some risk factors. The enrolled women visited Zakho Maternity Hospital from July 2018 to July 2019. Their ages ranged from 15 to 45 years. All samples were examined using ELISA to detect immunoglobulin G and M, in addition to performing IgG Avidity test for seropositive pregnant women. The differences between seropositivity and age was significant (p<0.05), the highest rate (20.43%) for anti-Toxoplasma IgG antibodies in the age group 33-38 years. Women who had more contact with cats showed higher IgG and IgM seropositivity rates (16.45% and 1.26%, respectively). Married women had higher IgG Abs seropositivity than single ones (12.52% vs 6.31%, respectively), moreover, only married women were seropositive for IgM Abs. Pregnant women presented higher IgG Abs seropositivity than non-pregnant (15.21% versus 10.49%), with almost equal seropositivity for IgM Abs (0.65% and 0.86%, respectively). Anti-Toxoplasma IgG Abs seropositivity was higher in women underwent miscarriages than those with normal pregnancies (18.44 vs. 8.81%), however IgM Abs was only found among women who had miscarriages (0.97%). Women with triple miscarriages presented the highest IgG Abs seropositivity (37.03%). Chronic infection was found in 68.75% of pregnant women, whereas acute infection was found in 31.25 %. Following up the pregnancy resulted in 15 healthy births, 9 miscarriages, and 10 women did not show up. The findings of this study demonstrate the relationship between toxoplasmosis and risk factors in women at childbearing age, with the aim of decreasing infection rates through the health education and application of hygienic measures.
2020

Seroprevalence of anti-Toxoplasma gondii antibodies among women of childbearing age in Zakho City KurdistanRegion of Iraq

2020-06
Zanco journal of pure and applied sciences (القضية : 3) (الحجم : 32)
A B S T R A C T: Toxoplasma gondii is the causative agent of toxoplasmosis. That makes serious health problems among immunocompromised patients which comprise pregnant women as well. The present study aimed to investigate the seroprevalence of anti-Toxoplasma gondii Antibodies among women of childbearing age and their associations to some demographic factors in Zakho City, Kurdistan Region/Iraq. Blood samples were collected randomly from 630 women aged 15-45 which were divided into subgroups (15-20), (21-26), (27-32), (33-38) and (39-45) years after taking their consent for the detection of anti-Toxoplasma IgG and IgM antibodies. A special questioner sheet was designed for the study containing full information about each participant. The diagnoses were done using ELISA-IgG and IgM kits and Rapid Test (RT) method. The prevalence of anti-Toxoplasma antibodies was 78/630 (12.38 %), including 73 (11.58 %) for ELISA IgG, 4 (0.63 %) for ELISA IgM and 1 (0.15 %) for RT method. The age group 33-38 years and married females showed the highest seroprevalence of 19/93 (20.43 %), 67/535 (12.52 %), respectively using ELISA IgG. Statically there were significant relations regarding ages, educational status, contact with cats and consumption of undercooked meat. This investigation indicated that the seroprevalence of anti-Toxoplasma antibodies among women at childbearing age is still a high rate. Furthermore, the association of some risk factors must be taken into consideration and this requires the introduction of health education programs to the community.

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